Webb10 feb. 2024 · In particular, the pursuit of knowledge of Cmax/MIC ratio is vital. On the other hand, this review demonstrates that the optimal Cmin for Japanese pediatric … WebbTwenty-five children with serious Gram-negative infections were treated in a prospective study with amikacin 20 mg/kg administered in a single daily dose as a 30 min iv infusion …

Therapeutic drug levels - GlobalRPH

Webb1 nov. 2024 · Amikacin is rapidly absorbed after intramuscular administration. In normal adult volunteers, average peak serum concentrations of about 12, 16, and 21 mcg/mL are obtained 1 hour after intramuscular administration of 250 mg (3.7 mg/kg), 375 mg (5 mg/kg), 500 mg (7.5 mg/kg), single doses, respectively. WebbIt was used as a combination therapy with carbapenems (69.2%) or aminoglycosides (80%). The median duration of treatment was 9 days (Range 1–50 days). Clinical and microbiological cure was observed in 110 cases (80%). Acute kidney injury developed during five treatment courses (4%) in which colistin was used in combination with … lightning sand sculptures for sale

Comparison of Amikacin Pharmacokinetics in Neonates Following ...

Webb• ECMO (normal dose range 15 <18 years: 20 mg/kg/dose IV q24h (normal dose range 15-30 mg/kg/dose IV q24h) ≥18 years: h-20 mg/kg/dose IV q24h) • If continuing past 48 … Webb30 juni 1986 · Combination antibiotic regimens that include an aminoglycoside such as amikacin continue to have an important role in pediatrics and should be used empirically … Webb18 juli 2024 · Amikacin is an antimicrobial with activity against more resistant gram-negative bacilli such as Acinetobacter baumanii and Pseudomonas aeruginosa. It also has excellent activity against most aerobic gram-negative bacilli from the Enterobacteriaceae family, including Nocardia sp. and some Mycobacterium spp. (M. avium-intracellulare, M. … peanut by-products