Mitomycin pulmonary toxicity
WebThe incidence of mitomycin-induced pulmonary toxicity has been reported to range from 2 to 38 percent. Concurrent vinca alkaloid administration may potentiate the risk of an acute … WebOther important side effects include pulmonary toxicity, which can occur with bleomycin, dactinomycin and mitomycin, and cardiotoxicity cardiac toxicity, which is a boxed …
Mitomycin pulmonary toxicity
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WebMitomycin-C (MMC) is an alkylating agent commonly used in chemotherapy . Lung toxicity and pulmonary venoocclusive disease (PVOD) are documented in patients taking MMC … Web1 jul. 1989 · Pulmonary arterial lesions were noted inconsistently in rats treated with BMY-26605, BMY-25282, and BMY-25551. Neither cardiac, renal, nor pulmonary changes …
WebMitomycin C–induced nephrotoxicity carries significant mortality, with associated pulmonary and neurological manifestations being the most common signs of poor … Web19 dec. 2011 · Drugs such as bleomycin, cyclophosphamide, nitrosureas, mitomycin, busulphan, and methotrexate commonly cause pulmonary toxicity but many other …
WebMitomycin is a chemotherapeutic agent that is used to treat a variety of solid tumors. Pulmonary toxic reactions from this agent can be life threatening. We prospectively … Web25 jul. 2024 · Pulmonary toxicity is a rare but well-documented adverse effect of mitomycin C. In one trial at the Mayo Clinic, despite pre …
Within all classes of medicinal drugs that possibly can lead to pulmonary toxicity as a side effect, most pulmonary toxicity is due to chemotherapy for cancer. Many medicinal drugs can lead to pulmonary toxicity. A few medicinal drugs can lead to pulmonary toxicity frequently (in medicine defined by international regulatory authorities such as the U.S. Food and Drug Administration and the EMEA [European Union] as > 1% and < 10%) or …
WebRespiratory symptoms improved in 3 patients following discontinuation of the drug. Two patients with extensive bilateral pneumonitis, who were not treated with steroids, died of … tearse bellinWebThe incidence of mitomycin-induced pulmonary toxicity has been reported to range from 2 to 38 percent. Concurrent vinca alkaloid administration may potentiate the risk of an acute … tear secretion testsWeb23 feb. 2024 · Although pulmonary and haematological toxicity has been reported following mitomycin C systemic administration, 3 there are very few documented cases … tears editing app