WebJul 7, 2024 · When caspases were cleaved and activated, they could release intracellular substances by forming pores on the cell membrane and eventually induce pyroptosis (16–19). In 2024, Shao’s team discovered that chemotherapy drugs induced cell death by cleaving GSDME through caspase-3 to induce pyroptosis . WebDownloadable (with restrictions)! Chemotherapy drugs can cause pyroptotic cell death by activating caspase-3 to cleave gasdermin E, potentially contributing to their toxicity and adverse effects.
Chemotherapy drugs induce pyroptosis through caspase-3
WebJan 27, 2024 · Dying cells activate pyroptosis through the following three main approaches: (i) ... Wang, Y. et al. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. WebSep 1, 2024 · Small-molecular-weight proteins, such as apoptin, have been shown to induce pyroptosis in cancer cells via the GSDME-dependent pathway . In addition to the classical ferroptosis inducer RSL3, chemotherapy drugs, such as cisplatin or nanoelicitor, were found to induce ferroptosis in tumor cells [64,102,103]. god of happiness hindu
Regulating GSDMB pore formation: to ignite or inhibit?
WebJul 27, 2024 · Inflammasomes induce pyroptosis through the canonical inflammasome pathway that depends on ... Gao W, Shi X, Ding J, Liu W, He H, et al. Chemotherapy drugs induce pyroptosis through caspase-3 ... WebPyroptosis-induced inflammation can trigger robust antitumor immunity and synergize with ... Wang Y, Gao W, Shi X, et al. Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin. ... Henning M, et al. Stromal Fibroblasts Induce CCL20 through IL6/C/EBPbeta to Support the Recruitment of Th17 Cells during Cervical Cancer ... WebAug 18, 2024 · Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin: 293: 2024: 0.00 : Open in a separate window. Open in a separate window. Figure 7. CiteSpace visualization map of top 50 references with the strongest citation bursts involved in pyroptosis. god of harlem saison 3